In 2020, the Jahani-Asl Lab in the Division of Experimental Medicine at McGill discovered that gene therapy techniques could make certain brain tumours more receptive to radiation treatment. Since then, the team has made yet another groundbreaking advancement—identifying a protein pathway that, when suppressed, could lead to reduced tumour growth.[Read More…]
Tag: Gene therapy
CRISPR-Cas9: The gene editing tool that has revolutionized molecular biology
It all began with bacteria: The observation and study of these single-celled organisms in the early 1980s allowed scientists to get a glimpse of the bacterial genome. In bacterial DNA, researchers found a class of repetitive nucleotide sequences, which they called Clusters of Regularly Interspaced Short Palindromic Repeats, or CRISPR.[Read More…]
Gene therapy provides a potential breakthrough in brain cancer treatment
In the fight against cancer, scientists have long grappled with the ambiguous nature of stem cells. Glioblastoma tumours, the most aggressive form of brain cancer in adults, consist of these cells, which have the notable ability to self-renew. This makes these tumours notoriously hard to treat with targeted radiation therapy[Read More…]